| Paolo Uccello | Italian Artist |
| Mark Udall | American Politician |
| Morris K. Udall | American Politician |
| Stewart L. Udall | American Politician |
| Tom Udall | American Politician |
| Peter Ueberroth | American Businessman |
| Bob Uecker | American Athlete |
| Brenda Ueland | American Writer |
| Nobuo Uematsu | Japanese Composer |
| Morihei Ueshiba | Japanese Athlete |
| Stanislaw Ulam | Polish Mathematician |
| Walter Ulbricht | German Politician |
| Liv Ullman | Norwegian Actress |
| Samuel Ullman | American Poet |
| Tracey Ullman | British Comedian |
| Liv Ullmann | Norwegian Actress |
| Walter F. Ulmer | |
| Lars Ulrich | Danish Musician |
| Skeet Ulrich | American Actor |
| Evelyn Underhill | English Writer |
| Blair Underwood | American Actor |
| Carrie Underwood | American Musician |
| Sigrid Undset | Norwegian Novelist |
| Gabrielle Union | American Actress |
| Moon Unit Zappa | American Musician |
| Johnny Unitas | American Athlete |
| Al Unser | American Athlete |
| Bobby Unser | American Celebrity |
| Louis Untermeyer | American Poet |
| John Updike | American Novelist |
| Fred Upton | American Politician |
| Karl Urban | |
| Keith Urban | American Musician |
| Midge Ure | Scottish Musician |
| Alvaro Uribe Velez | Colombian Statesman |
| Robert Urich | American Actor |
| Leon Uris | American Writer |
| Hans Urs von Balthasar | Swiss Theologian |
| Peter Ustinov | English Actor |
| Peter Utley |